Neurodegeneration and Epileptic Seizure: Earlier Than We Think
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Original Article
VOLUME: 28 ISSUE: 4
P: 149 - 151
December 2022

Neurodegeneration and Epileptic Seizure: Earlier Than We Think

Arch Epilepsy 2022;28(4):149-151
1. Department of Neurology, Dokuz Eylül University Hospital, İzmir, Turkey
No information available.
No information available
Received Date: 03.10.2022
Accepted Date: 27.12.2022
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ABSTRACT

Objective:

The purpose of this study is to compare demographical and cognitive features of patients who have neurodegenerative diseases with or without seizures.

Methods:

This descriptive retrospective study included a total of 16 348 participants, 479 with seizures and 15 869 without seizures. Independent samples t-test and chi-square tests were used to compare age, education, Mini Mental State Examination, and gender of groups.

Results:

There was a significant difference between patients with seizures and without seizures in age [t(3764) = 2.815, P = .005]. It is found that patients with seizures (M = 67.51, standard deviation = 9.69) were significantly younger than patients without seizures (M = 70.37, standard deviation = 9.51).

Conclusion:

In all neurodegenerative diseases, especially Alzheimer’s disease, at an early age and regardless of cognitive status, diagnosis of seizures at the first admission and subsequent follow-ups is of great importance in terms of the patient’s quality of life, prognosis of the disease, and treatment options.

Keywords:
Cognition, dementia, epilepsy, neurodegeneration, neurology, seizure.